Effects of electromagnetic radiation
from GSM mobile phone
on DNA and stress proteins and
biological protection through CMO-Tecno AO
(compensatory magnetic oscillation)
2003
Commentary, summary and extracts of key points from the article by Professor Reba Goodman in 2003 published in the Journal of Cellular Biochemistry : Effects of mobile phone radiation on reproduction and development in Drosophila melanogaster “
Effects of mobile phone radiation on reproduction and development in Drosophila melanogaster
David Weisbrot 1, Hana Lin 2, Lin Ye 1, Martin Blank 3, Reba Goodman 1
1Department of Pathology, Columbia University Health Sciences,
2Department of Anatomy, Columbia University Health Sciences,
3Department of Physiology, Columbia University Health Sciences, 630 West 168 St. NYC, New York 10032
Journal of Cellular Biochemistry. Volume 89, Issue 1, 2003. pages: 48-55
Professor R. Goodman (Dept of Pathology – Columbia University Health Sciences- New York) is one of the world experts in genetics and the study of biological effects of electromagnetic fields on DNA.
In particular, she has done much work and published on the changes in stress proteins activity (Heat Shock Proteins or HSP) in relation to the exposure of organisms or cellular cultures of different types to electromagnetic fields (EMF).
These proteins are omnipresent throughout evolution, from the most primitive bacteria to man. In evolved organisms, HSP are present in all tissue as well as in cytoplasm, in mitochondria, in endoplasmic reticulum or the cell nucleus. As the name indicates : Heat Shock Proteins, « proteins of thermal shock », HSPs are synthesised following stress or shock.
If thermal shock was the first known factor capable of inducing the synthesis of these proteins, a host of other factors that cause the production of HSP have been identified since their discovery in the 70s. Oxidants and free radicals, certain heavy metals, ethanol, metabolic poisons (arsenic), a lack of glucose, etc….all induce the synthesis of HSP in cell culture systems.
ELF electromagnetic radiation, even of low intensity, also induces their synthesis. (cf. Goodman magnetic field of 60Hz on man)
HSPs are involved in many physiological or physiopathological processes, in many very varied situations, all of which makes it difficult to take a simple view of their role, since their functions cover very different fields.
It is possible to say that HSPs have two mutually contradictory roles : ” The « good » HSP, which have many beneficial functions, such as the control of the folding of proteins, called the role of a chaperone with the prevention or correction of the denaturation and agglomeration of proteins with its opposite, the « bad » HSP which are involved in some physiopathological processes such as autoimmune illnesses, infectious sicknesses and bacterial virulence factors ; they are also involved in prion diseases.”
All HSP are markers of cell distress. In effect, the higher the expression of these proteins, the greater the stress.
On the genetic level, it is the activation of the gene c-myc which causes the synthesis of HSP 70 proteins. HSP 70 protein increases when the organism is in the presence of toxins and is therefore considered as a significant marker for the evaluation of environmental pollution.
Professor Goodman’s team has studied certain DNA chains and has previously demonstrated the activation of the genes c-myc, c-fos and c-jun following the exposure of organisms to radio frequencies or to extremely low frequency (ELF) radiation at very low intensities, so ruling out any possibility of thermal effects.
These three genes, c-myc, c-fos and c-jun, also have an important role in the regulation and control of the development of organisms and are known to be involved in the cells carcinogen process.
The study of these factors of cell growth is also crucial to the evaluation of electromagnetic pollution, since their regulation by the growth hormone (GH) correlates to the general development of the organism, its metabolism, the death and renewal of cells, and in certain conditions, the promotion of cancerous cells. This growth activity is controlled by the genes c-fos and c-jun, through the DNA controlling sequence called SRE (Serum Response Element).
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